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The previously reported cytotoxic metabolites, against the KB cell line, xestoquinone, halenaquinol sulfate and halenaquinol 5,6 were isolated from the unidentified sponge collected in October 1992, Manado Bay, Sulawesi in Indonesia. Their structure were elucidated by 1H-,13C-NMR, 1H-,13C (1 bond) Heteronuclear Multiple Quantum Coherence Spectroscopy(HMQC) 1,1H-,13C (2 and 3 bond) Heteronuclear multiple Bond Correlation Spectroscopy (HMBC)2, Electron Impact Mass Spectroscopy(EI ms), Ultraviolet Spectroscopy(UV), and Infrared Spectroscopy(IR)
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